Dr. Julie Hussin is an associate professor in the Department of Medicine and Department of Biochemistry, Université de Montréal (UdeM). She leads the bioinformatics group MHI-OMICS at the Montreal Heart Institute (MHI) and is an associate academic member at Mila, Quebec Artificial Intelligence Institute. Julie was trained in computational biology and statistical and population genetics. Her projects now encompass the fields of biomedical science and artificial intelligence for health.

Dr Hussin is the chair of the graduate bioinformatics programs at UdeM. She teaches bioinformatics, population genetics and machine learning for genomics and health research.  

How to Reach Me

Contact : julie.hussin [at] umontreal.ca

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Representative Publications

Richard-St-Hilaire A, Gamache I, Pelletier J, Grenier JC, Poujol R, Hussin JG. 2024. Signatures of selection, co-evolution and co-regulation in the CYP3A and CYP4F genes in humans. Genome Biology and Evolution.

Baron C, Cherkaoui S, Therrien-Laperriere S, Ilboudo Y, Poujol R, Mehanna P, Garrett ME, Telen MJ, Ashley-Koch AE, Bartolucci P, Rioux JD, Lettre G, Des Rosiers C, Ruiz M, Hussin JG. 2023. Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results. iScience.

Scicluna M, Grenier JC, Poujol R, Lemieux S, Hussin JG. 2023. Towards Computing Attributions for Dimensionality Reduction Techniques. Bioinformatics Advances.

Hamelin D, Fournelle D, Grenier JC, Schockaert J, Kovalchik K, Kubiniok P, Mostefai F, Duquette JD, Saab F, Sirois I, Smith MA, Pattijn S, Soudeyns H, Decaluwe H, Hussin JG*, Caron E*. 2022. The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA supertype-dependent manner. Cell Systems. (*co-senior)

Gamache I, Legault MA, Grenier JC, Sanchez R, Rhéaume E, Asgari S, Barhdadi A, Feroz Zada Y, Trochet H, Luo Y, Lecca L, Murray M, Raychaudhuri S, Tardif JC, Dubé MP, Hussin JG. 2021. A sex-specific evolutionary interaction between ADCY9 and CETP. eLife.

Ben Ali W°, Pesaranghader A°, Avram R, Overtchouk P, Perrin N, Laffite S, Cartier R, Ibrahim, R, Modine T*, Hussin JG*. 2021. Implementing Machine Learning in Interventional Cardiology: The Benefits are Worth the Trouble. Frontiers in Cardiovascular Medicine. (°co-first authors, *co-senior)

Samman K, Mehanna P, Takla E, Grenier JC, Chan MY, Lopes RD, Lee Neely M, Wang TY, Newby LK, Becker RC, Lordkipanidzé M, Ruiz M, Hussin JG°,* and Jolicoeur ME°. 2021. Differential modulation of polyunsaturated fatty acids in patients with myocardial infarction treated with ticagrelor or clopidogrel. Cell Reports Medicine. (°co-senior, *corresponding)

Romero A, Carrier PL, Erraqabi A, Sylvain T, Auvolat A, Dejoie E, Legault MA, Dubé MP, Hussin JG*, Bengio Y*. 2017. Diet networks: thin parameters for fat genomics. 5th International Conference on Learning Representations (ICLR) 2017. (*co-senior)

Davies B, Hatton EW, Altemose N, Hussin JG, Pratto F, Zhang G, Moralli D, Hinch AG, Biggs D, Diaz R, Preece C, Brick K, Green C, Camerini-Otero RD, Myers SR, Donnelly P. 2016. Re-engineering the zinc fingers of Prdm9 reverses hybrid sterility in mice. Nature

Hussin JG, Hodgkinson A, Idaghdour Y, Grenier JC, Goulet JP, Gbeha E, Hip-Ki E, Awadalla P. 2015. Recombination affects accumulation of damaging and disease-associated mutations in human populations. Nature Genetics

Hussin J., Sinnett D., Casals F. Idaghdour Y, Bruat V, Saillour V, Healy J, Grenier JC, de Malliard T, Busche S, Spinella JF, Lariviere M, Gibson G, Andersson A, Holmfeldt L, Ma J, Wei L, Zhang J, Andelfinger G, Downing JR, Mullighan CG, Awadalla P. Rare allelic forms of PRDM9 associated with childhood leukemia. Genome Research.

(Full list here)

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